Dr. ÁDÁM STURM

 

Research           

Aging; DNA methylation (epigenetics); CRISPR / Cas9 techniques;

             Deep-neural networks, Molecular cloning, Bioinformatics,

             Next-generation sequencing

 

   Experiences            

Semmelweis University (Institute for Pathology and Experimental Cancer Research, Number I, 2016-)

Examination of the role of transposons in cancer

 

Velgene Three Kft. (2014 - 2016)

Examination of the role of transposons in cancer

 

ELTE MSc and PhD (Department of Genetics, 2012 -)

Research on the theory of aging based on transposable elements and development of RNA interference and Cas9 / CRISPR in C. elegans. Deep neural network development

 

MTA TTK (Biomembrane Group, 2013 - 2016)

Developing CRISPR / Cas9 techniques

 

Paul-Ehrlich-Institut (Department of Medical Biotechnology, 2013)

Research and cooperation on aging theory based on transposable elements

MTA SZTAKI

Deep neural network development. Convolution machine learning and gradient boosting development

Deep Biotech Solutions Ltd.

Deep neural network, Cas9 / CRISPR, Molecular cloning,

Bioinformatics, Next-generation sequencing

             Studies                   

             ELTE TTK PhD (2013-2019)

             Department of Genetics

 

             ELTE TTK MSc (2012-2013)

             Molecular Genetics, Cell and Development Science

                                       

              ELTE TTK BSc (2007–2012)

              Biology

              Publications           

1.         Sturm, A., Ivics, Z. and Vellai, T. (2015) The mechanism of ageing: primary role of transposable elements in genome disintegration. Cellular and molecular life sciences : CMLS, 72, 1839-1847.

2.         Sturm, A., Perczel, A., Ivics, Z. and Vellai, T. (2017) The Piwi-piRNA pathway: road to immortality. Aging cell, 16, 906-911.

3.         Sturm, A., Saskoi, E., Tibor, K., Weinhardt, N. and Vellai, T. (2018) Highly efficient RNAi and Cas9-based auto-cloning systems for C. elegans research. Nucleic Acids Research, Manuscript ID NAR-02888-Met-G-2017.R1  

4.         Talas, A., Kulcsar, P.I., Weinhardt, N., Borsy, A., Toth, E., Szebenyi, K., Krausz, S.L., Huszar, K., Vida, I., Sturm, A. et al. (2017) A convenient method to pre-screen candidate guide RNAs for CRISPR/Cas9 gene editing by NHEJ-mediated integration of a 'self-cleaving' GFP-expression plasmid. DNA research : an international journal for rapid publication of reports on genes and genomes.

5.         Csaba Kerepesi, Bálint Daróczy, Ádám Sturm, Tibor Vellai & András Benczúr (2018) Prediction and characterization of human ageing-related proteins by using machine learning. Scientific reports. doi:10.1038/s41598-018-22240-w        

6.         Sturm, Á., Saskői, É., Hotzi, B. et al. Downregulation of transposable elements extends lifespan in Caenorhabditis elegans. Nat Commun 14, 5278 (2023). https://doi.org/10.1038/s41467-023-40957-9