Curriculum vitae - Tibor Vellai

16 December, 2021

Name: Tibor Vellai

Birth place, date:      Budapest (Hungary), 13 May, 1967

Nationality:    Hungarian

Home address: 1125 Budapest, Mátyás király út 38/C/1, Mobile: (+36)-20-571-2239

Diploma:        Biologist, Eötvös Loránd University (ELTE), Faculty of Sciences, 1987-1992 (124/92)

Degree:           Ph.D., ELTE, TTK - 1999 (P-185/1999; Genetics)

D.Sc., (Hungarian Academy of Sciences - HAS) (5028/2011)

Languages:    Englishangol (medium level), French (basic level), Russian (basic)

Present working place, position:

professor, head of department, Department of Genetics, Eötvös Loránd University, Budapest, Hungary (1117 Budapest, Pázmány Péter stny. 1/C., Hungary Tel.: (+36)-1-372-2500 Ext: 8684, Fax: (+36)-1-372-2641, mobile: +36-20-5712239; E-mail: vellai.tibor@ttk.elte.hu, vellai.tibor@gmail.com

Carrier:

            Research Fellow (HAS-ELTE;1992-1995)

            PhD student (ELTE; 1993-1999)

            Research Fellow (Collegium Budapest; 1998-1999)

Assistant lecturer (Department of Genetics, ELTE; 1999-2003)

Postdoctoral Fellow (University of Fribourg, Institute of Zoology, Switzerland; 1999-2003)

            Assistant professor (Department of Genetics, ELTE; 2003-2004)

            Associate professor (Department of Genetics, ELTE; 2004-2013)

            Habilitated associate professor (Department of Genetics, ELTE; 2007-2013)

            Full professor (Department of Genetics, ELTE; 2013-)              

Teaching activity: lectures and practices in genetics, developmental genetics, microbial genetics, molecular biology, RNA interference for biologists and teachers and medical students.

MSc/Bsc supervisor: >100 (ELTE, University of Fribourg)

Ph.D. supervisor: 14 completed and 10 ongoing (ELTE, Doctoral School of Biology)

Research topics: regulation of early development by Hox genes; sex-determination and dosage compensation; cell death; autophagy; aging; DNA methylation (epigenetics); neuronal degeneration; identification of drug candidates; signaling crosstalk (bioinformatics)

Public scientific activity:

  • reviewer for scientific journals from 2002- (e.g., J Mol Evol; Trends Parasitol; Proc Roy Soc Lond B; Trends Cell Biol; BMC Genomics; Autophagy; Physiology; Eur J Cell Biol; WormBook; PloS Genet; Zool Res.; BMC Dev Biol; BMC Biol; Cell Death Disease; Age; Cancer Cell Int; Acta Veter Hung; Nature, Nat Aging)
  • Editorial board member:
    • Zoological Research (2008-)
    • BMC Developmental Biology (2008-2012)
    • Autophagy (2008-2014)
    • FEBS Open Biol (2015-2018)
    • Scientifica (2017)
    • ISRN Entomology (2018)
  • Secretary general of Hungarian Genetic Society (2016-)
  • Co-chair of the Molecular Biology, Genetics and Cell Biology Committee, HAS (2016-)
  • Chair of the professor committee, Institute of Biology, ELTE; 2019-
  • Leader of program genetics, Doctoral School of Biology, ELTE; 2013-
  • Vice chair of the Doctoral School of Biology, ELTE; 2020-
  • Leader of genetic research group, HAS-ELTE, 2017-
  • Advisory board member of the Bolyai Research Grant, HAS, 2012-

Awards:

  • Bolyai Research Grant plaquette (2012)
  • Eminent teacher of the university (2014)
  • Innovative researcher awards, ELTE (2015, 2020)
  • Excellence award of the rector, ELTE (2016)

Grants: 25 (around 4 M EUR in total)

Publications:

Articles in peer reviewed journals: 80

Top level/high standard publications: Nature (2), Nat Commun, Nat Struc Mol Biol, Proc Natl Acad Sci USA, Autophagy; Nucleic Acids Res, Trends Cell Biol, Genetics, Development

Book chapters (English): 2

Independent citations: 8422 (MTMT - https://m2.mtmt.hu/gui2/?mode=search&query=author;label;any;vellai%20tibor); total citations: 14001 (MTMT) / 23600 (Google Scholar)

H-index: 32 (MTMT) / 48 (Google Scholar)

Patent applications: 4

Publication list (in the order of publication date) - Tibor VELLAI

(15 December, 2021)                                                  

Original research paper (peer-reviewed)

  1. Vellai T, Takács K, Vida G. A new aspect to the origin and evolution of eukaryotes. J. Mol. Evol. 46(5): 499–507 (1998). (IF: 3.271)
  2. Triga D, Pamjav H, Vellai T, Fodor A, Buzás Z. Gel electrophoretic restriction fragment lenght polymorphism analysis of DNA derived from individual nematodes, using the PhastSystem. Electrophoresis 20(6): 1274–1279 (1999). (IF: 3.447)
  3. Pamjav H, Triga D, Buzas Z, Vellai T, Lucskai A, Adams B, Reid AP, Burnell A, Griffin C, Glazer I, Klein MG, Fodor A. Novel application of PhastSystem polyacrylamide gel electrophoresis using restriction fragment lenght polymorphism - internal transcribed spacer patterns of individuals for molecular identification of entomopathogenic nematodes. Electrophoresis 20(6): 1266–1273 (1999). (IF: 3.447)
  4. Vellai T, Vida G. The origin of eukaryotes: the difference between prokaryotic and eukaryotic cells. Proc. R. Soc. Lond. B Biol. Sci. 266(1428): 1571–1577 (1999). (IF: 2.755)
  5. Vellai T, Kovács AL, Kovács G, Ortutay C, Vida G. Genome economization and a new approach to the species concept in bacteria. Proc. R. Soc. Lond. B Biol. Sci. 266(1432): 1953–1959 (1999). (IF: 2.755)                                                          
  6. Ortutay C, Gáspári Z, Tóth G, Jáger E, Vida G, Orosz L, Vellai T (2003). Speciation in Chlamydia: Genomewide phylogenetic analyses identified a reliable set of acquired genes. J. Mol. Evol. 57(6): 672–680 (2003). (IF: 3.114)
  7. Vellai T, Takács-Vellai K, Zhang Y, Kovács AL, Orosz L, Müller F. Influence of TOR kinase on lifespan in C. elegans. Nature 426(6967): 620 (2003). (IF: 30.979)
  8. Menzel O*, Vellai T*, Takács-Vellai K, Reymond A, Mueller F, Antonarakis SE, Guipponi M. The Caenorhabditis elegans ortholog of C21orf80, a potential new protein O-fucosyltransferase, is required for normal development. Genomics 84(2): 320–330 (2004). (IF: 3.84) *Contributed equally
  9. Takács-Vellai K, Vellai T, Puoti A, Passannante M, Wicky C, Streit A, Kovács AL, Müller F. Inactivation of the autophagy gene bec-1 triggers apoptotic cell death in C. elegans. Curr. Biol. 15(16): 1513–1517 (2005). (IF: 11.732)
  10. Vellai T, McCulloch D, Gems D, Kovács AL. Effects of sex and insulin/IGF-1 signaling on performance in an associative learning paradigm in Caenorhabditis elegans. Genetics 174(1): 309–316 (2006). (IF: 4.242)
  11. Takács-Vellai K, Bayci A, Vellai T. Autophagy in neuronal cell loss: a road to death. BioEssays 28(11): 1126–1131 (2006). (IF: 5.965)
  12. Szöllősi GJ, Derényi I, Vellai T. The maintenance of sex in bacteria is ensured by its potential to reload genes. Genetics 174(4): 2173–2180 (2006). (IF: 4.242)
  13. Takács-Vellai K, Vellai T*, Chen EB, Zhang Y, Guerry F, Stern MJ, Müller F. Transcriptional control of Notch signaling by a HOX and a PBX/EXD protein during vulval development in C. elegans. Dev. Biol. 302(2): 661–669 (2007). (IF: 4.714) *Corresponding author
  14. Tóth ML, Simon P, Kovács AL, Vellai T. Influence of autophagy genes on ion channel-dependent neuronal degeneration in Caenorhabditis elegans. J. Cell Sci. 120(6): 1134–1141 (2007). (IF: 6,383)
  15. Vellai T, Tóth ML, Kovács AL. Janus-faced autophagy. A dual role of cellular self-eating in neurodegeneration? Autophagy 3(5): 461–463 (2007). (IF: 4.657)
  16. Aladzsity I, Tóth ML, Sigmond T, Szabó E, Bicsák B, Barna J, Regős Á, Orosz L, Kovács AL, Vellai T. Autophagy genes unc-51 and bec-1 are required for normal cell size in Caenorhabditis elegans. Genetics 177(1): 655–660 (2007). (IF: 4.001)
  17. Kovács AL, Pálfia Z, Réz G, Vellai T, Kovács J. Sequestration revisited. Integrating traditional electron microscopy, de novo assembly and new results. Autophagy 3(6): 655–662 (2007). (IF: 4.657)
  18. Klionsky DJ, …, Vellai T, …, Deter RL. Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy 4(2): 151–175 (2008). (IF: 5.479)
  19. Kassai-Jáger E, Ortutay C, Tóth G, Vellai T, Gáspári Z. Distribution and evolution of short tandem repeats in closely related bacterial genomes. Gene 410(1): 18–25 (2008). (IF: 2,578)
  20. Tóth ML, Sigmond T, Borsos É, Barna J, Erdélyi P, Takács-Vellai K, Orosz L, Kovács AL, Csikós G, Sass M, Vellai T. Longevity pathways converge on autophagy genes to regulate life span in Caenorhabditis elegans. Autophagy 4(3): 330–338 (2008). (IF: 5.479)
  21. Vellai T, Bicsák B, Tóth ML, Takács-Vellai K, Kovács AL. Regulation of cell growth by autophagy. Autophagy 4 (4): 507–509 (2008). (IF: 5.479)
  22. Sigmond T, Barna J, Tóth ML, Takács-Vellai K, Pásti G, Kovács AL, Vellai T. Autophagy in Caenorhabditis elegans. Method Enzymol. 451: 521–540 (2008). (IF: 2.312)
  23. Sigmond T, Fehér J, Baksa A, Pásti G, Pálfia Z, Takács-Vellai K, Kovács J, Vellai T, Kovács AL. Qualitative and quantitative characterization of autophagy in Caenorhabditis elegans by electron microscopy. Method. Enzymol. 451: 467–491 (2008). (IF: 2.312)
  24. Vellai T. Autophagy genes and ageing. Cell Death Differ. 16(1): 94–102 (2009). (IF: 8,24)
  25. Borsy A, Podani J, Stéger V, Balla B, Kósa J, Gyurján I, Molnár A, Szabolcsi Z, Szabó L, Jáko E, Zomborszky Z, Nagy J, Semsey S, Vellai T, Lakatos P, Orosz L. Identifying novel genes involved in both deer physiological and human pathological osteoporosis. Mol. Genet. Genomics 281(3): 301–313 (2009). (IF: 2.579)
  26. Szabó E, Hargitai B, Regős Á, Tihanyi B, Barna J, Borsos É, Takács-Vellai K, Vellai T (2009). TRA-1/GLI controls the expression of the Hox gene lin-39 during C. elegans vulval development. Dev. Biol. 330(2): 339–348 (2009). (IF: 4.379)
  27. Vellai T, Takács-Vellai K, Sass M, Klionsky DJ. The regulation of aging: does autophagy underlie longevity? Trends Cell Biol. 19(10): 487–494 (2009). (IF: 12.115)
  28. Hargitai B, Kutnyánszky V, Blauwkamp TA, Steták A, Csankovszki G, Takács-Vellai K, Vellai T. xol-1, the master sex switch gene in C. elegans, is a transcriptional target of the terminal sex-determining factor TRA-1/GLI. Development 136(23): 3881–3887 (2009). (IF: 7.194)
  29. Vellai T, Klionsky DJ. A second report from the EMBO conference on autophagy: mechanism, regulation and selectivity of autophagy. Autophagy 6(1): 197–198 (2010). (IF: 6,643)                                                                      
  30. Tihanyi B, Vellai T*, Regős Á, Ari E, Müller F, Takács-Vellai K. The C. elegans Hox gene ceh-13 functions in a non-colinear way to regulate cell migration and fusion. Implications for the origin of Hox clusters. BMC Dev. Biol. 10: 78 (2010). (IF: 3.29) *Corresponding author.
  31. Korcsmáros T, Farkas IJ, Szalay MS, Rovó P, Fazekas D, Spiró Z, Böde C, Lenti K, Vellai T, Csermely P. Uniformly curated signaling pathways reveal tissue-specific cross-talks and drug target candidates. Bioinfomatics 26(16): 2042–2050 (2010). (IF: 4.877)
  32. Vellai T, Takács-Vellai K. Regulation of protein turnover by longevity pathways. Adv. Exp. Med. Biol. 694: 69–80 (2010). (IF: 2.02)
  33. Erdélyi P, Borsos É, Takács-Vellai K, Kovács T, Kovács AL, Sigmond T, Hargitai B, Pásztor L, SenGupta T, Dengg M, Pécsi I, Tóth J, Nilsen H, Vértessy BG, Vellai T. Shared developmental roles and transcriptional control of autophagy and apotosis in C. elegans. J. Cell Sci. 124(9): 1510–1518 (2011). (IF: 6.111)
  34. Borsos É, Erdélyi P, Vellai T. Autophagy and apoptosis are redundantly required for C. elegans embryogenesis. Autophagy 7(5): 557–559 (2011). (IF: 7.453)
  35. Farkas IJ, Korcsmáros T, Kovács IA, Mihalik Á, Palotai R, Simkó GI, Szalay KZ, Szalay-Bekő M, Vellai T, Wang S, Csermely P. Network-based tools in the identification of novel drug-targets. Sci. Signal. 4, pt3 (2011). (IF: 7.499)
  36. Korcsmáros T, Szalay MS, Rovó P, Palotai R, Lenti K, Farkas IJ, Csermely P, Vellai T. Signalogs: orthology-based identification of novel signaling pathway components in three metazoans. PLoS ONE 6(5): e19240 (2011). (IF: 4,092)
  37. Várkuti B, Yang Z, Kintses B, Erdélyi P, Bárdos-Nagy I, Kovács AL, Hári P, Kellermayer M, Vellai T, Málnási-Csizmadia A. A novel actin binding site of myosin required for effective muscle contraction. Nat. Struct. Mol. Biol. 19(3): 299–306 (2012). (IF: 12.712)
  38. Klionsky DJ, …, Vellai T, …, Zuckerbraun B.. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy 8(4): 445–544 (2012). (IF: 7.453)
  39. Barna J, Princz A, Kosztelnik M, Hargitai B, TakácsVellai K, Vellai T. Heat shock factor-1 intertwines insulin/IGF-1, TGF-β and cGMP signaling to control development and aging. BMC Dev. Biol. 12: 32 (2012). (IF: 2.79)
  40. Regős Á, Lengyel K, Takács-Vellai K, Vellai T. Identification of novel cis-regulatory regions from the Notch receptor genes lin-12 and glp-1 of Caenorhabditis elegans. Gene Expr. Patterns 13(3-4): 66–77 (2013). (IF: 2.037)
  41. Fazekas D, Koltai M, Türei D, Módos D, Pálfy M, Dúl Z, Zsákai L, Szalay-Bekő M, Lenti L, Farkas IJ, Vellai T, Csermely P, Korcsmáros T. SignaLink 2 – A signaling pathway resource with multi-layered regulatory networks. BMC System Biol. 7(1): 7 (2013). (IF: 3.15)
  42. Korcsmáros T, Dunai ZA, Vellai T, Csermely P. Teaching the bioinformatics of signaling networks – an integrated approach to facilitate multidisplinary learning. Brief Bioinform. 14(5): 618–632 (2013). (IF: 5.202)
  43. Masoudi N, Fancsalszky L, Pourkarimi E, Vellai T, Alexa A, Reményi A, Gartner A, Mehta A, Takács-Vellai K. The Nm23-H1/H2 homolog NDK-1 is required for full activation of Ras signaling in C. elegans. Development 140(16): 3486–3495 (2013). (IF: 6.273)
  44. Varga M, Sass M, Papp D, Takács-Vellai K, Klionsky DJ, Vellai T. Autophagy is required for zebrafish caudal fin regeneration. Cell Death Differ. 21(4): 547–556 (2013). (IF: 8.184)
  45. Pálfy M, Farkas IJ, Vellai T, Korcsmáros T. Uniform curation protocol of metazoan signaling pathways to predict novel signaling components. Methods Mol. Biol. 1021: 285–297 (2013). (PMID: 23715991, IF: 1.29)
  46. Kubisch J, Türei D, Földvári-Nagy L, Dunai ZA, Zsákai L, Varga M, Vellai T, Csermely P, Korcsmáros T. Complex regulation of autophagy in cancer – integrated approaches to discover the networks that hold a double-edged sword. Semin. Cancer Biol. 23(4): 252–261 (2013). (PMID: 23810837, IF: 9.143)
  47. Sengupta T, Torgersen ML, Kassahun H, Vellai T, Simonsen A, Nilsen H. Base excision repair AP-endonucleases and mismatch repair act together to induce checkpoint mediated autophagy. Nat. Commun. 4: 2674 (2013). (PMID: 24154628, IF: 10,742)
  48. Fancsalszky L, Monostori E, Farkas Z, Pourkarimi E, Masoudi N, Hargitai B, Bosnar MH, Deželjin M, Zsákai A, Vellai T, Mehta A, Takács-Vellai K. NDK-1, the homolog of NM23-H1/H2 regulates cell migration and apoptotic engulfment in C. elegans. PLoS One 9(3): e92687 (2014). (PMID: 24658123, IF: 3.234)
  49. Földvári-Nagy L, Ari E, Csermely P, Korcsmáros T, Vellai T. Starvation-response may not involve Atg1-dependent autophagy induction in non-unikont parasites. Sci. Rep. 4: 5829 (2014). (PMID: 25059978, IF: 5.578)
  50. Varga M, Fodor E, Vellai T. Autophagy in zebrafish. Methods 75: 172–180 (2015). (PMID: 25498006, IF: 3.645)
  51. Takács-Vellai K, Vellai T, Farkas Z, Mehta A. Nucleoside diphosphate kinases (NDPKs) in animal development. Cell. Mol. Life Sci. 72(8): 1447–1462 (2015). (PMID: 25537302, IF: 5.808)
  52. Türei D, Földvári-Nagy L, Fazekas D, Módos D, Kubisch J, Kadlecsik T, Demeter A, Lenti K, Csermely P, Vellai T, Korcsmáros T. Autophagy Regulatory Network - a systems-level bioinformatics resource for studying the mechanism and regulation of autophagy. Autophagy 11(1): 155–165 (2015). (PMID: 25635527, IF: 11.753)
  53. Sturm Á, Ivics Z, Vellai T. The mechanism of ageing: primary role of transposable elements in genome disintegration. Cell. Mol. Life Sci. 72(10): 1839–1847 (2015). (PMID: 25837999, IF: 5.808)
  54. Papp D, Kovács T, Billes V, Varga M, Tarnóci A, Hackler L Jr, Puskás LG, Liliom H, Tárnok K, Schlett K, Borsy A, Pádár Z, Kovács AL, Hegedűs K, Juhász G, Komlós M, Erdős A, Gulyás B, Vellai T. AUTEN-67, an autophagy-enhancing drug candidate with potent antiaging and neuroprotective effects. Autophagy 12(2): 273–286 (2015). (PMID: 26312549, IF: 9.108)
  55. Klionsky DJ, …, Vellai T, …, Zughaier SM. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy 12(1): 1–222 (2016). (PMID: 26799652, IF: 9.108)
  56. Csályi K, Fazekas D, Kadlecsik T, Türei D, Gul L, Horváth B, Módos D, Demeter A, Pápai N, Lenti K, Csermely P, Vellai T, Korcsmáros T, Varga M. SignaFish: A Zebrafish-Specific Signaling Pathway Resource. Zebrafish 13(6): 541–544 (2016). (PMID: 27097230, IF: 2,175).
  57. Billes V, Kovács T, Hotzi B, Manzéger A, Tagscherer K, Komlós M, Tarnóci A, Pádár Z, Erdős A, Bjelik A, Legradi A, Gulya K, Gulyás B, Vellai T. AUTEN-67 (Autophagy Enhancer-67) Hampers the Progression of Neurodegenerative Symptoms in a Drosophila model of Huntington's Disease. J. Huntingtons Dis. 5(2): 133–147 (2016). (PMID: 27163946, IF: 1.58)
  58. Modos D, Brooks J, Fazekas D, Ari E, Vellai T, Csermely P, Korcsmaros T, Lenti K. Identification of critical paralog groups with indispensable roles in the regulation of signaling flow. Sci. Rep. 6: 38588 (2016). (PMID: 27922122, IF: 5.228)
  59. Harami GM, Seol Y, In J, Ferencziová V, Martina M, Gyimesi M, Sarlós K, Kovács ZJ, Nagy NT, Sun Y, Vellai T, Neuman KC, Kovács M. Shuttling along DNA and directed processing of D-loops by RecQ helicase support quality control of homologous recombination. Proc. Natl. Acad. Sci. USA. 114(4): E466–E475 (2017). (PMID: 28069956, IF: 9.423)
  60. Kovács T, Billes V, Komlós M, Hotzi B, Manzéger A, Tarnóci A, Papp D, Szikszai F, Szinyákovics J, Rácz Á, Noszál B, Veszelka S, Walter FR, Deli MA, Hackler L Jr, Alfoldi R, Huzian O, Puskas LG, Liliom H, Tárnok K, Schlett K, Borsy A, Welker E, Kovács AL, Pádár Z, Erdős A, Legradi A, Bjelik A, Gulya K, Gulyás B, Vellai T. The small molecule AUTEN-99 (autophagy enhancer-99) prevents the progression of neurodegenerative symptoms. Sci. Rep. 7: 42014 (2017). (PMID: 28205624, IF: 4.122)
  61. Fodor E, Sigmond T, Ari E, Lengyel K, Takács-Vellai K, Varga M, Vellai T. Methods to study autophagy in zebrafish. Methods Enzymol. 588: 467–496 (2017). (PMID: 28237116, IF: 2,088)
  62. Gyuris M, Hackler L Jr, Nagy LI, Alföldi R, Rédei E, Marton A, Vellai T, Faragó N, Ózsvári B, Hetényi A, Tóth GK, Sipos P, Kanizsai I, Puskás LG. Mannich Curcuminoids as Potent Anticancer Agents. Arch. Pharm. (Weinheim). 350(7) (2017). (PMID: 28547897, IF: 2.288)
  63. Módos D, Bulusu KC, Fazekas D, Kubisch J, Brooks J, Marczell I, Szabó PM, Vellai T, Csermely P, Lenti K, Bender A, Korcsmáros T. Neighbours of cancer-related proteins have key influence on pathogenesis and could increase the drug target space for anticancer therapies. NPJ Syst. Biol. Appl. 3: 2 (2017). PMID: 28603644
  64. Sturm Á, Perczel A, Ivics Z, Vellai T. The Piwi-piRNA pathway: road to immortality. Aging Cell 16(5): 906–911 (2017). (PMID: 28653810, IF: 7.627)
  65. Ferencziová V, Harami GM, Németh JB, Vellai T, Kovács M. Functional fine-tuning between bacterial DNA recombination initiation and quality control systems. PLoS One 13(2): e0192483 (2018). (PMID: 29470542, IF: 2.766)
  66. Hotzi B, Kosztelnik M, Hargitai B, Takács-Vellai K, Barna J, Bördén K, Málnási-Csizmadia A, Lippai M, Ortutay C, Bacquet C, Pasparaki A, Arányi T, Tavernarakis N, Vellai T. Sex-specific regulation of aging in Caenorhabditis elegans. Aging Cell 17(3): e12724 (2018). (PMID: 29493066, IF: 7.627)
  67. Kapuy O, Papp D, Vellai T, Bánhegyi G, Korcsmáros T (2018). Sstems-Level Feedbacks of NRF2 Controlling Autophagy upon Oxidative Stress Response. Antioxidants (Basel). 7(3). pii: E39 (2018). (PMID: 29510589, IF: 4.52)
  68. Kerepesi C, Daróczy B, Sturm Á, Vellai T, Benczúr A. Prediction and characterization of human ageing-related proteins by using machine learning. Sci. Rep. 8(1): 4094 (2018). (PMID: 29511309, IF: 4.122)
  69. Barna J, Csermely P, Vellai T. Roles of heat shock factor 1 beyond the heat shock response. Cell. Mol. Life Sci. 75(16): 2897–2916 (2018). (PMID: 29774376, IF: 6,721)
  70. Sturm Á, Saskoi É, Tibor K, Weinhardt N, Vellai T. Highly efficient RNAi and Cas9-based auto-cloning systems for C. elegans research. Nucleic Acids Res. 46(17): e105 (2018). (PMID: 29924347, IF: 11.561)
  71. Billes V, Kovács T, Manzéger A, Lőrincz P, Szincsák S, Regős Á, Kulcsár PI, Korcsmáros T, Lukácsovich T, Hoffmann G, Erdélyi M, Mihály J, Takács-Vellai K, Sass M, Vellai T. Developmentally regulated autophagy is required for eye formation in Drosophila. Autophagy 14(9): 1499–1519 (2018). (PMID: 29940806, IF: 11.1)
  72. Kosztelnik M, Kurucz A, Papp D, Jones E, Sigmond T, Barna J, Traka MH, Lorincz T, Szarka A, Banhegyi G, Vellai T, Korcsmaros T, Kapuy O. Suppression of AMPK/aak-2 by NRF2/SKN-1 down-regulates autophagy during prolonged oxidative stress. FASEB J. 33(2): 2372–2387 (2018). (PMID: 30277819, IF: 5.595)
  73. Rakvács Z, Kucsma N, Gera M, Igriczi B, Kiss K, Barna J, Kovács D, Vellai T, Bencs L, Reisecker JM, Szoboszlai N, Szakács G. The human ABCB6 protein is the functional homologue of HMT-1 proteins mediating cadmium detoxification. Cell. Mol. Life Sci. 76(20): 4131–4144 (2019). (PMID: 31053883, IF: 7.014)
  74. Kovács D, Sigmond T, Hotzi B, Bohár B, Fazekas D, Deák V, Vellai T, Barna J. HSF1Base: A comprehensive database of HSF1 (Heat Shock Factor 1) target genes. Int. J. Mol. Sci. 20(22) pii: E5815 (2019). (PMID: 31752429, IF: 4.183)
  75. Kutnyánszky V, Hargitai B, Hotzi B, Kosztelnik M, Ortutay C, Kovács T, Győry E, Bördén K, Princz A, Tavernarakis N, Vellai T. Sex-specific regulation of neuronal functions in Caenorhabditis elegans: the sex-determining protein TRA-1 represses goa-1/Gα(i/o). Mol. Genet. Genomics. 295(2): 357–371 (2019). (PMID: 31776761, IF: 2.685)
  76. Pápai N, Kagan F, Csikós G, Kosztelnik M, Vellai T, Varga M. No correlation between endo- and exoskeletal regenerative capacities in Teleost species. Fishes 4(4): 51 (2019)
  77. Klionsky DJ, …, Vellai T, …, Tong CK. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy 17(1): 1–382 (2021). (PMID: 33634751, IF: 16.016)
  78. Szente L, Puskás I, Vellai T, Lohmann H. Effects of alpha-cyclodextrin on water transport, cell hydration and longevity. Aging (Albany NY). 13(2): 1718–1728 (2021). (PMID: 33468711, IF: 5.682)
  79. Manzéger A, Tagscherer K, Lőrincz P, Szaker H, Lukácsovich T, Pilz P, Kméczik R, Csikós G, Erdélyi M, Sass M, Kovács T, Vellai T, Billes VA. Condition-dependent functional shift of two Drosophila Mtmr lipid phosphatases in autophagy control. Autophagy. 28: 1–19 (2021). (PMID: 33779490, IF: 16.016)
  80. Vellai T. How the amino acid leucine activates the key cell-growth regulator mTOR. Nature 596(7871): 192–194 (2021). (PMID: 34290413, IF: 49.962) 
  81. Csabai L, Fazekas D, Kadlecsik T, Szalay-Bekő M, Bohár B, Madgwick M, Módos D, Ölbei M, Gul L, Sudhakar P, Kubisch J, Oyeyemi OJ, Liska O, Ari E, Hotzi B, Billes VA, Molnár E, Földvári-Nagy L, Csályi K, Demeter A, Pápai N, Koltai M, Varga M, Lenti K, Farkas IJ, Türei D, Csermely P, Vellai T, Korcsmáros T.SignaLink3: a multi-layered resource to uncover tissue-specific signaling networks. Nucleic Acids Res. gkab909 online (2021). (PMID: 34634810, IF: 16.971) 

Book chapter

  1. Kovács AL, Vellai T, Müller F (2004). Autophagy in Caenorhabditis elegans. In: Autophagy, ed. Daniel J. Klionsky, Landes Bioscience, Georgetown, Texas, USA, pp. 219-225.
  2. Vellai T, Takács-Vellai K (2009). Regulation of protein turnover by longevity pathways. In: Protein synthesis and aging, ed. Nektarios Tavernarakis, Landes Bioscience, Georgetown, Texas, USA, pp69-80.
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