Dr. Bernadette Hotzi
Her main research interest is the genetic regulation of ageing, including several subtopics (sex-specific aspects, transposons, N6-adenine methylation). Her other important research topic is the genetic regulation of behaviour (sex-specific behaviour, sleep). She is also involved in investigating the role of HSF -1 in stress responses. She uses C. elegans model organism for her researches.
Call: +36-1-372-2500 /Ext. 8349 E-mail: bernadette.hotzi@ttk.elte.hu
Publication list:
Kovács, D*, Sigmond, T*, Hotzi, B*, Bohár, B, Fazekas, D, Deák, V, Vellai, T, Barna, J.
HSF1Base: A Comprehensive Database of HSF1 (Heat Shock Factor 1) Target Genes, International Journal of Molecular Science, (2019)
(*: megosztott első szerző)
Kutnyánszky, V.*, Hargitai, B.*, Hotzi, B*, Kosztelnik, M., Ortutay Cs., Kovács, T., Győry, E., Bördén, K., Princz, A., Tavernarakis, N. and Vellai, T., Sex-specific regulation of neuronal functions in Caenorhabditis elegans, Molecular Genetics and Genomics (2019) (*: megosztott első szerző
Hotzi, B., Kosztelnik, M., Hargitai, B., Takács-Vellai, K., Barna, J., Bördén, K., Málnási-Csizmadia, A., Lippai, M., Ortutay, C., Bacquet, C., Pasparaki, A., Arányi, T., Tavernarakis, N. and Vellai, T. 2018. Sex-specific regulation of aging in Caenorhabditis elegans. Aging Cell 17(3), p. e12724.
Kovács, T., Billes, V., Komlós, M., Hotzi, B., Manzéger, A., Tarnóci, A., Papp, D., Szikszai, F., Szinyákovics, J., Rácz, Á., Noszál, B., Veszelka, S., Walter, F.R., Deli, M.A., Hackler, L., Alfoldi, R., Huzian, O., Puskas, L.G., Liliom, H., Tárnok, K. and Vellai, T. 2017. The small molecule AUTEN-99 (autophagy enhancer-99) prevents the progression of neurodegenerative symptoms. Scientific Reports 7, p. 42014.
Billes, V., Kovács, T., Hotzi, B., Manzéger, A., Tagscherer, K., Komlós, M., Tarnóci, A., Pádár, Z., Erdős, A., Bjelik, A., Legradi, A., Gulya, K., Gulyás, B. and Vellai, T. 2016. AUTEN-67 (Autophagy Enhancer-67) Hampers the Progression of Neurodegenerative Symptoms in a Drosophila model of Huntington’s Disease. Journal of Huntington’s Disease 5(2), pp. 133–147.